human sclc cell line h69 Search Results


nci-h69 human small cell lung cancer (sclc) cell line  (National Centre for Cell Science)
90
National Centre for Cell Science nci-h69 human small cell lung cancer (sclc) cell line
Nci H69 Human Small Cell Lung Cancer (Sclc) Cell Line, supplied by National Centre for Cell Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nci-h69 human small cell lung cancer (sclc) cell line/product/National Centre for Cell Science
Average 90 stars, based on 1 article reviews
nci-h69 human small cell lung cancer (sclc) cell line - by Bioz Stars, 2026-03
90/100 stars
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nci-h69 (a human sclc cell line)  (Procell Inc)
90
Procell Inc nci-h69 (a human sclc cell line)
PTPMT1 knockdown reduces cell growth in A549 cells. PTPMT1 mRNA expression (A) and protein level (B) were significantly decreased in PTPMT1-shRNA-transfected cells. (C) CCK-8 assay for cell proliferation of PTPMT1-shRNA-transduced A549. (D) CCK-8 assay for cell proliferation of PTPMT1-shRNA-transduced <t>H69</t> cells. ***, P<0.001, vs . scramble (control). PTPMT1, protein tyrosine phosphatase mitochondrial 1; mRNA, messenger RNA; CCK-8, cell counting kit 8; shRNA, short-hairpin RNA.
Nci H69 (A Human Sclc Cell Line), supplied by Procell Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nci-h69 (a human sclc cell line)/product/Procell Inc
Average 90 stars, based on 1 article reviews
nci-h69 (a human sclc cell line) - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

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PTPMT1 knockdown reduces cell growth in A549 cells. PTPMT1 mRNA expression (A) and protein level (B) were significantly decreased in PTPMT1-shRNA-transfected cells. (C) CCK-8 assay for cell proliferation of PTPMT1-shRNA-transduced A549. (D) CCK-8 assay for cell proliferation of PTPMT1-shRNA-transduced H69 cells. ***, P<0.001, vs . scramble (control). PTPMT1, protein tyrosine phosphatase mitochondrial 1; mRNA, messenger RNA; CCK-8, cell counting kit 8; shRNA, short-hairpin RNA.

Journal: Translational Cancer Research

Article Title: PTPMT1 inhibition induces apoptosis and growth arrest of human SCLC cells by disrupting mitochondrial metabolism

doi: 10.21037/tcr-2024-2379

Figure Lengend Snippet: PTPMT1 knockdown reduces cell growth in A549 cells. PTPMT1 mRNA expression (A) and protein level (B) were significantly decreased in PTPMT1-shRNA-transfected cells. (C) CCK-8 assay for cell proliferation of PTPMT1-shRNA-transduced A549. (D) CCK-8 assay for cell proliferation of PTPMT1-shRNA-transduced H69 cells. ***, P<0.001, vs . scramble (control). PTPMT1, protein tyrosine phosphatase mitochondrial 1; mRNA, messenger RNA; CCK-8, cell counting kit 8; shRNA, short-hairpin RNA.

Article Snippet: NCI-H69 (a human SCLC cell line) was purchased from Procell (Wuhan, China) and cultured in 1640 medium (Gibco, Waltham, MA, USA) supplemented with 10% fetal bovine serum (FBS) (Gibco).

Techniques: Knockdown, Expressing, shRNA, Transfection, CCK-8 Assay, Control, Cell Counting

PTPMT1 inhibition induces cell death in A549 cells. (A,B) The percentage of apoptosis in the A549 and H69 cells transduced with PTPMT1-shRNA or control shRNA assessed by annexin-V assay and flow cytometry. ***, P<0.0001, sh-PTPMT1 vs . scramble (control). (C) The cell viability of A549 cells treated with alexidine dihydrochloride in the presence of Fer-1. (D) The cell viability of H69 cells treated with alexidine dihydrochloride in the presence of Fer-1. ns, no significance; **, P<0.01, alexidine dihydrochloride 2.5 µM vs . control (DMSO); ***, P<0.001, alexidine dihydrochloride 5 µM/10 µM vs . control (DMSO). PTPMT1, protein tyrosine phosphatase mitochondrial 1; shRNA, short-hairpin RNA; DMSO, dimethylsulfoxide.

Journal: Translational Cancer Research

Article Title: PTPMT1 inhibition induces apoptosis and growth arrest of human SCLC cells by disrupting mitochondrial metabolism

doi: 10.21037/tcr-2024-2379

Figure Lengend Snippet: PTPMT1 inhibition induces cell death in A549 cells. (A,B) The percentage of apoptosis in the A549 and H69 cells transduced with PTPMT1-shRNA or control shRNA assessed by annexin-V assay and flow cytometry. ***, P<0.0001, sh-PTPMT1 vs . scramble (control). (C) The cell viability of A549 cells treated with alexidine dihydrochloride in the presence of Fer-1. (D) The cell viability of H69 cells treated with alexidine dihydrochloride in the presence of Fer-1. ns, no significance; **, P<0.01, alexidine dihydrochloride 2.5 µM vs . control (DMSO); ***, P<0.001, alexidine dihydrochloride 5 µM/10 µM vs . control (DMSO). PTPMT1, protein tyrosine phosphatase mitochondrial 1; shRNA, short-hairpin RNA; DMSO, dimethylsulfoxide.

Article Snippet: NCI-H69 (a human SCLC cell line) was purchased from Procell (Wuhan, China) and cultured in 1640 medium (Gibco, Waltham, MA, USA) supplemented with 10% fetal bovine serum (FBS) (Gibco).

Techniques: Inhibition, Transduction, shRNA, Control, Annexin V Assay, Flow Cytometry

PTPMT1 inhibition reduces Glut expression. (A-E) The qRT-PCR analysis of the transcriptome differentially sequenced genes in H69 cells. *, P<0.05; **, P<0.01; ***, P<0.001, AD 5 µM vs . control (DMSO). (F,G) The H69 cells were transduced with PTPMT1 shRNA. The expression of Glut1 and Glut3 was determined by qRT-PCR. ***, P<0.001, sh-PTPMT1 vs . scramble (control). (H) The H69 cells were transduced with PTPMT1-shRNA or control vectors, and stained with JC-1 dye, and the ratio of the average fluorescence intensity of red/green was determined by flow cytometry. ***, P<0.001, sh-PTPMT1 vs . scramble (control). PTPMT1, protein tyrosine phosphatase mitochondrial 1; qRT-PCR, quantitative real-time polymerase chain reaction; shRNA, short-hairpin RNA; DMSO, dimethylsulfoxide; AD, alexidine dihydrochloride; mRNA, messenger RNA.

Journal: Translational Cancer Research

Article Title: PTPMT1 inhibition induces apoptosis and growth arrest of human SCLC cells by disrupting mitochondrial metabolism

doi: 10.21037/tcr-2024-2379

Figure Lengend Snippet: PTPMT1 inhibition reduces Glut expression. (A-E) The qRT-PCR analysis of the transcriptome differentially sequenced genes in H69 cells. *, P<0.05; **, P<0.01; ***, P<0.001, AD 5 µM vs . control (DMSO). (F,G) The H69 cells were transduced with PTPMT1 shRNA. The expression of Glut1 and Glut3 was determined by qRT-PCR. ***, P<0.001, sh-PTPMT1 vs . scramble (control). (H) The H69 cells were transduced with PTPMT1-shRNA or control vectors, and stained with JC-1 dye, and the ratio of the average fluorescence intensity of red/green was determined by flow cytometry. ***, P<0.001, sh-PTPMT1 vs . scramble (control). PTPMT1, protein tyrosine phosphatase mitochondrial 1; qRT-PCR, quantitative real-time polymerase chain reaction; shRNA, short-hairpin RNA; DMSO, dimethylsulfoxide; AD, alexidine dihydrochloride; mRNA, messenger RNA.

Article Snippet: NCI-H69 (a human SCLC cell line) was purchased from Procell (Wuhan, China) and cultured in 1640 medium (Gibco, Waltham, MA, USA) supplemented with 10% fetal bovine serum (FBS) (Gibco).

Techniques: Inhibition, Expressing, Quantitative RT-PCR, Control, Transduction, shRNA, Staining, Fluorescence, Flow Cytometry, Real-time Polymerase Chain Reaction